Insights into Obesity

In clinical practice, obesity is assessed by BMI, and visceral fat accumulation (indicator for higher cardiovascular risk) can be assessed by waist circumference WC. An inclusive history, physical examination and laboratory evaluation related to the patient's obesity must be acquired. A comprehensive obesity management could be achieved only by a multidisciplinary obesity management team.Lifestyle modifications, pharmacotherapy, and bariatric surgery are the main lines of obesity treatment. Lifestyle interventions, have been demonstrated to be the least effective. Intensive behavioral interventions combined with dietary modifications and improved physical activity can lead to > 5% weight loss in obese adults.Pharmacological treatment (Orlistat, Liraglutide, Phentermine/Topiramate, Naltrexon/Buproprion, & Locaserin,) have very restricted efficacy, particularly in individuals with morbid obesity. Bariatric surgery such as sleeve gastrectomy SG and Roux-en-Y gastric bypass; is the most effective but most invasive therapy for morbid obesity.