Introduction to Protein Science: Architecture, Function, and Genomics

Bol Partner

Proteins are essential to life, having a great variety of roles in all organisms. They are the ultimate micro-machines: some are building blocks, joining with other substances to make the cells from which we are formed; some are catalysts, speeding up biochemical reactions to keep our cells active and alive; yet others help cells to communicate, to move, to build up the complex mix of tissues that make up our bodies, and to regulate unfolding programmes of development. Introduction to Protein Science provides a broad ranging introduction to the contemporary study of proteins in health and disease, suitable for students on biological, biochemical, and biomedical degrees internationally. It relates the study of proteins to the context of modern high-throughput data streams of genomics and proteomics. Describing basic principles of protein structure and methods for studying them, the book illustrates the wide variety of functions that proteins have, showing how the structures of proteins are intimately linked to their functions. Building on the success of the first edition, the new edition integrates treatment of bioinformatics, databases and computational methods of determining and predicting protein structure and function, and demonstrates how these methods are paving the way for the ability to design novel proteins with specific desired characteristics. With added coverage of recent developments in the field, particularly in high-throughput methods; a new chapter on enzyme kinetics; extended coverage of topics such as protein evolution, and the immune system; as well as the inclusion of new end-of-chapter exercises, problems and weblems, the book captures the current state of excitement in a way that all biosciences students and instructors will find appealing. Online Resource Centre The Online Resource Centre to accompany Introduction to Protein Science features the following resources for lecturers and students. For registered adopters - Figures from the book available to download - Answers to end-of-chapter exercises For students - Links to useful websites to aid further research into protein science - Helpful hints and tips for answering end-of-chapter problems

Bol

Written by a leading author in the field, Introduction to Protein Science provides a wide-ranging perspective on the study of protein structure and function in the context of bioinformatics and genomics. Opportunities for active learning are provided both in the text and online, enabling students to develop their problem solving skills. Over the last century, the centrality of proteins to life on earth has become increasingly clear - from forming enzymes acting as catalysts for specific reactions, to crucial molecules such as antibodies in the immune system, and as signalling molecules between cells. In fact, the more they are studied, the more proteins continue to reveal new and exciting functions. Indeed, by studying amino acid sequences and protein structures it is even possible to unravel some of the mysteries of evolution itself. Introduction to Protein Science, 3rd edition provides a rich and broad introduction to this fascinating field by covering not only the structure and function of proteins, but also the methods and experimental techniques used to study them. The practical applications of our knowledge to diverse fields such as biotechnology and medicine are emphasized throughout, to help students appreciate the relevance of the subject to the real world. Active learning is encouraged by the provision of frequent exercises and problems, with further 'weblems' - web-based problems - on the Online Resource Centre. Online Resource Centre The Online Resource Centre to accompany Introduction to Protein Science features: For students: ·Answers to end-of-chapter exercises, and hints to end-of-chapter problems, so students can check their understanding. ·Rotating structures from the book to help students visualize proteins in 3D. ·Web-based problems for students to complete online. For registered adopters: ·Figures from the book in electronic format, ready to download

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Pagina's: 488, Editie: 3 Revised edition, Paperback, Oxford University Press