100 Essential Papers on Anorexia(Anorexia Nervosa): For Psychiatrists and Allied Professionals: 6

100 Essential Papers on Anorexia NervosaAnorexia nervosa (AN), sometimes referred to as anorexia, is far more than a disorder of "not being able to eat" or "becoming dangerously thin."It is a complex illness that extends well beyond the boundaries of psychiatry, involving life-threatening medical complications, refeeding syndrome, suicide risk, family dynamics, comorbid obsessive-compulsive disorder and autism spectrum disorder, as well as genetic, neurological, and metabolic factors.This volume, part of the 100 Essential Medical Papers series, carefully selects 105 landmark studies that have shaped the history of anorexia nervosa and eating-disorder research, explaining their key findings in a clear and accessible way.Topics covered include: - Diagnosis, epidemiology, and long-term outcomes of anorexia nervosa - Atypical anorexia nervosa - Mortality, suicide, and self-harm - Medical complications involving the cardiovascular system, kidneys and electrolytes, endocrine system, bone health, pregnancy, and more - Refeeding syndrome and safer approaches to nutritional rehabilitation - Family-Based Treatment (FBT) for adolescents - Psychological therapies including CBT-E, MANTRA, and SSCM - Pharmacological treatments including olanzapine and SSRIs - Virtual reality, Cognitive Remediation Therapy (CRT), and Deep Brain Stimulation (DBS) - Comorbidity with autism spectrum disorder, OCD, depression, and PTSD - Severe and Enduring Anorexia Nervosa (SE-AN) - Ethical controversies surrounding compulsory treatment, palliative care, and the concept of "terminal anorexia nervosa" - Healthcare disparities, barriers to treatment, and health economics - Genome-wide association studies (GWAS), neuroimaging, cognition, the gut microbiome, and multi-omics researchThe book includes a wide range of studies that have changed both clinical practice and scientific thinking: randomized controlled trials of Family-Based Treatment for adolescent AN; the StRONG trial, which challenged conventional assumptions about refeeding; ANTOP, comparing major psychotherapeutic approaches for adults with AN; a large randomized trial of olanzapine; meta-analyses demonstrating the elevated mortality associated with eating disorders; and landmark genome-wide association studies that helped redefine anorexia nervosa as a "metabo-psychiatric disorder."Together, these papers trace the evolution of anorexia nervosa from a narrowly defined psychiatric diagnosis to a complex disorder at the intersection of psychiatry, internal medicine, nutrition, neuroscience, genetics, and metabolism.This book is intended not only for physicians, psychologists, nurses, dietitians, clinical psychologists, medical students, and residents involved in eating-disorder care, but for anyone who wishes to develop a deeper, evidence-based understanding of anorexia nervosa.