Acute Toxicology Poisoning & Overdose Handbook: Clinical Diagnosis, Toxidromes, Antidotes, ECG Clues, Decontamination, and Critical Care Management

When poisoning or overdose is suspected, the most valuable knowledge is the kind that helps turn uncertainty into structured clinical action. From the first unstable presentation to the final disposition decision, acute toxicology demands rapid recognition, disciplined reasoning, and a clear understanding of what changes management.Acute Toxicology: Poisoning & Overdose Handbook is a premium clinical reference designed to bring together the diagnostic patterns, physiologic principles, antidotes, emergency interventions, and high-risk exposures that define modern toxicologic care. Organized around real clinical decisions, it guides the reader from initial stabilization and toxidrome recognition through ECG interpretation, targeted testing, decontamination, enhanced elimination, critical care, and safe disposition.Inside, readers will find: - A structured approach to the poisoned patient, including initial stabilization, toxidromes, diagnostic clues, acid-base interpretation, toxicologic ECG findings, and the limitations of common laboratory testing.- Practical management of major overdoses and poisonings, including acetaminophen, salicylates, opioids, antidepressants, cardiovascular drugs, toxic alcohols, pesticides, metals, household chemicals, and natural toxins.- Antidotes and advanced rescue strategies, with clinically focused discussion of naloxone, N-acetylcysteine, fomepizole, sodium bicarbonate, high-dose insulin therapy, chelation, extracorporeal toxin removal, and other targeted interventions.- Modern toxicology beyond traditional exposures, including fentanyl adulterants, novel psychoactive substances, xylazine, emerging synthetic drugs, severe agitation, hyperthermia, envenomation, and critical-care toxicology.The handbook emphasizes the questions that matter at the bedside: What is the immediate threat? Which findings narrow the diagnosis? Which test will change management? When is an antidote indicated? When is dialysis or advanced support required? How long should the patient be observed?With a clear clinical structure, full-color presentation, focused visual material, and a strong emphasis on recognition, treatment, reassessment, and disposition, Acute Toxicology is designed to become a practical reference for emergency medicine, critical care, toxicology, pharmacy, medical training, and any setting where poisoning and overdose must be understood quickly and managed systematically.Recognize the pattern. Stabilize the physiology. Treat the toxin. Reassess the patient. Make the next decision with confidence.