Pediatric allergic diseases are a major public health concern worldwide. This phenomenon could be influenced by climate change, a growing challenge of the 21st century. Our work aims to describe the epidemiological evolution of clinical and allergenic profiles in atopic children in Tunisia between 1992-2022 and to assess the impact of climate change on the clinical and allergenic characteristics of this population.Methods:We conducted a retrospective study analyzing data from the last 30 years from the digital archive of the allergology unit at FSI La Marsa Hospital. Our series included children aged from 1 to 16 years, who underwent skin testing. Meteorological data from the Tunis-Carthage station were extracted from an online database. Epidemiological analysis was based on a comparison of 3 decades: D1 (1992-2001), D2 (2002-2011) and D3 (2012-2022).
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