Aryl Hydrocarbon Receptor
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109,21 |
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109,21 |
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156,00 |
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Beschrijving
Bol
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The Aryl hydrocarbon receptor is a member of the family of basic-helix-loop-helix transcription factors. AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. Upon ligand binding to chemicals such as 2,3,7,8-tetrachlorodibenzo-p-dioxin, the chaperones dissociate resulting in AhR translocating into the nucleus and dimerizing with ARNT, leading to changes in gene transcription.
Beschrijving
(1)
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The Aryl hydrocarbon receptor is a member of the family of basic-helix-loop-helix transcription factors. AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. Upon ligand binding to chemicals such as 2,3,7,8-tetrachlorodibenzo-p-dioxin, the chaperones dissociate resulting in AhR translocating into the nucleus and dimerizing with ARNT, leading to changes in gene transcription.
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