Breast cancer in Souk Ahras: a regional reality: Understanding its epidemiological, biological and biochemical characteristics

Breast cancer remains the leading cause of cancer mortality in women in Algeria. In this context, our study aims to analyze the epidemiological, biological and biochemical characteristics of breast cancer in patients followed in two areas of the Souk Ahras wilaya: Souk Ahras center and Sedrata. We conducted a retrospective descriptive study based on medical records. Data collected included hormone receptors (ER, PR), HER2 status, Ki-67 proliferation index, as well as biological parameters (haematology, liver enzymes, CA 15-3).results show that tumours in Sedrata are predominantly hormone-sensitive (83.3%), with moderate Ki-67 and a higher frequency of HER2+ tumours, reflecting a generally more favourable biological profile. In Souk Ahras, on the other hand, a predominance of triple-negative tumors (35.3%) and a high Ki-67 (70.6%) were observed, indicating a more aggressive phenotype.