Flow Cytometry in Drug Discovery and Development

Apply flow cytometry to drug discovery and development The growth of immunotherapy and cellular therapies has dramatically expanded flow cytometry's role in drug development, while, in parallel, advances in single-cell analysis have transformed the field. Now in its Second Edition, Flow Cytometry in Drug Discovery and Development focuses on pharmaceutical applications, helping translational scientists apply flow cytometry and helping cytometrists understand the pharmaceutical applications. Where other references concentrate on general laboratory protocols or instrument specifications, this book targets the intersection of single-cell analysis and drug development. It equips readers to evaluate drug and therapy quality using high-content analytical techniques including multiparametric analysis of single cells. Readers will also find: Guidance on applying simultaneous multiparametric single-cell analysis to pharmaceutical quality assessment and therapeutic development programs Updated content reflecting the dramatic expansion of immunotherapy and cellular therapy applications since the first edition Practical frameworks connecting flow cytometry techniques to specific stages within the drug discovery and development pipeline Coverage of related technologies advancing single-cell analysis beyond conventional flow cytometry for drug development contexts Perspectives relevant to professionals across academia, contract research organizations, biotech, and pharmaceutical industry settings Designed for pharmaceutical and biotech scientists, analytical chemists, clinical investigators, bioengineers, and university researchers, this Second Edition serves professionals working at the intersection of single-cell analysis and drug development. Instrument vendors supporting drug development workflows will also find it a targeted resource. Apply flow cytometry to drug discovery and development The growth of immunotherapy and cellular therapies has dramatically expanded flow ??cytometry’s role in drug development, while, in parallel, advances in single-cell analysis have transformed the field. Now in its Second Edition, Flow Cytometry in Drug Discovery and Development focuses on pharmaceutical applications, helping translational scientists apply flow cytometry and helping cytometrists understand the pharmaceutical applications. Where other references concentrate on general laboratory protocols or ??instrument specifications, this book targets the intersection of single-cell analysis and drug development. It equips readers to evaluate drug and therapy quality using high-content analytical techniques including multiparametric analysis of single cells. Readers will also find: Guidance on applying simultaneous multiparametric single-cell analysis to pharmaceutical quality assessment and therapeutic development programs Updated content reflecting the dramatic expansion of immunotherapy and cellular therapy applications since the first edition Practical frameworks connecting flow cytometry techniques to specific stages within the drug discovery and development pipeline Coverage of related technologies advancing single-cell analysis beyond conventional flow cytometry for drug development contexts Perspectives relevant to professionals across academia, contract research organizations, biotech, and pharmaceutical industry settings Designed for pharmaceutical and biotech scientists, analytical chemists, clinical ??investigators, bioengineers, and university researchers, this Second Edition serves professionals working at the intersection of single-cell analysis and drug development. Instrument ??vendors ??supporting drug development workflows will also find it a targeted resource.