Medicinal Chemistry and Drug Development

Medicinal Chemistry and Drug Development describes the key events and roles of medicinal chemistry in the discovery and development of lead compounds into drugs, including target identification, which is accomplished by using 30 case studies. This book outlines all the stages of drug development, including the discovery of active compounds, research on the pharmacologicalproperties of molecules, and confirmation of drug targets. The role of the case studies is to show the common factors in the successful development of drugs, thereby showing medicinal chemists how best to explore the scientific pathways when developing new drugs. This makes the book especially relevant for senior university students majoring in pharmaceutical sciences as well as graduate students and researchers. - Provides unique information on different drug development case studies - Integrates pharmaceutical knowledge—mainly medicinal chemistry—with new drug development thinking - Describes using case studies, the impact of key events in drug development and on drug efficacy