Molecular Basis of Head & Neck Oncology

Head and neck cancers occupy a unique intersection of biology, medicine, and human experience. They arise in regions essential for breathing, speech, swallowing, and sensory perception, which means their impact is often felt early. Behind each visible tumor lies a complex and largely invisible molecular landscape-genetic disruptions, epigenetic alterations, abnormal signaling pathways, and microenvironmental changes that drive the transformation of normal cells into malignant ones.This book begins within that molecular space where oncogenesis originates. In recent decades, advances in science have significantly transformed our understanding of how head and neck cancers develop and progress. Once viewed mainly through anatomical and histopathological perspectives, these cancers are now recognized as diseases shaped by identifiable molecular mechanisms. Discoveries such as the role of high-risk human papillomavirus in certain oropharyngeal cancers, insights from high-throughput sequencing into mutational landscapes, and a deeper understanding of tumor-immune interactions have reshaped the narrative of oncogenesis.

Pagina's: 88, Paperback, LAP LAMBERT Academic Publishing