Molecular Biomarkers and More Efficient Therapies for Sepsis

Sepsis remains a leading cause of morbidity and mortality worldwide, underscoring the urgent need for advances in diagnosis, prognostication, and therapeutic strategies. This Special Issue gathers high-quality contributions exploring the various molecular biomarkers and novel therapeutic approaches aimed at improving outcomes in sepsis. The articles cover a wide spectrum of topics, including the identification of early diagnostic indicators, molecular pathways driving immune dysregulation, host-pathogen interactions, and targeted interventions based on biomarker profiles. Both preclinical and clinical studies are included, highlighting translational potential and real-world applications. By emphasizing precision medicine and individualized treatment strategies, this collection offers valuable insights for clinicians, researchers, and policy-makers seeking to combat the global burden of sepsis. The findings presented in this Special Issue contribute to a deeper understanding of disease mechanisms and open new avenues for more efficient and personalized sepsis care.