This Special Issue reprint showcases cutting-edge research on natural products as sources of innovative therapeutics. Contributions explore the discovery, pharmacological characterization, and clinical potential of bioactive compounds from traditional medicine, aromatic plants, and probiotics. Key topics include molecular mechanisms of disease prevention, neg-entropy (biological order enhancement) in treatment, essential oils, gut microbiota modulation, and safety profiles. The reprint integrates multidisciplinary approaches to advance drug development from nature's chemical diversity.
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