NBS in Peptide Chemistry: Synthesis, Kinetics & Mechanisms: Oxidative Transformations and Reaction Pathways

This book presents a comprehensive account of the kinetics, mechanisms, and oxidative transformations mediated by N-bromosuccinimide (NBS), with particular emphasis on amino acids, peptides, and model polypeptide systems. Beginning with fundamental principles of chemical kinetics and reaction mechanisms, the text systematically reviews the chemistry of NBS as a versatile oxidizing and brominating agent in both aqueous and non-aqueous media. Detailed discussions are provided on oxidative decarboxylation, peptide bond cleavage, and selective transformations involving biologically relevant functional groups. Experimental kinetic data are critically analyzed to elucidate reaction pathways, rate laws, and the role of medium effects, catalysts, and substrate structure. The work further highlights the relevance of NBS-mediated oxidation processes in biochemical contexts, including peptide modification and degradation. By integrating classical literature with systematic kinetic investigations, this volume serves as a valuable reference for researchers and postgraduate students in physical chemistry, organic chemistry, and peptide chemistry.

Pagina's: 120, Paperback, LAP LAMBERT Academic Publishing