New Advances in Neuroimmunology and Neuroinflammation

Increasing evidence points to strong immunological and inflammatory components in various neurological and neuropsychiatric diseases. Understanding the underlying mechanisms and functions of these immune and inflammatory responses is crucial for advancing our knowledge of conditions like Parkinson's disease, Alzheimer's, mental disorders, and amyotrophic lateral sclerosis (ALS). A great number of clinical trails have failed to successfully address the issue of neuroinflammation and its complex orchestrated response that harnesses age-related diseases. Therefore, the exact role of neuroimmunology and neuroinflammation requires extensive investigation. This Special Issue of Brain Sciences aims to showcase recent advances in neuroimmunology and neuroinflammation research in both preclinical and clinical areas, with a focus on neurodegenerative diseases. This Special Issue offers insights into in vivo and in vitro studies on new concepts, technological innovations, and novel models that can be applied to explore the role of neuroimmunology and neuroinflammation in neurological and neuropsychiatric diseases. This includes (but is not limited to), the role of inflammation in blood-brain barrier dysfunction, the effects of new drugs to treat neurodegenerative diseases and their role in the immune response, and the mediating effects of anti-inflammatory therapies in neurodegeneration.