Non Superimposable Approach for Construction Of Two Tetrahydrofuran Rings 15 Carbon Chain A Class Natural Products, C14 C29 Fragment The Anticancer Agent Halaven And Laurencia Metabolites

Name: Non Superimposable Approach for Construction Of Two Tetrahydrofuran Rings 15 Carbon Chain A Class Natural Products, C14 C29 Fragment The Anticancer Agent Halaven And Laurencia Metabolites
SKU: d2ce3ba1627cd0c62d4dc33abb5455a8
Price: 33.99 EUR
Availability: InStock

1/1

Afbeelding van Non Superimposable Approach for Construction Of Two Tetrahydrofuran Rings 15 Carbon Chain A Class Natural Products, C14 C29 Fragment The Anticancer Agent Halaven And Laurencia Metabolites

Bol

Prijzen vanaf

33,99

Uitgelicht

	33,99	Naar shop
VERGELIJK ALLE AANBIEDERS (1)

Beschrijving

Bol Five membered ring alicyclic compounds are thermodynamically most stable compounds due to their reduced interior angle strain (bond angle is ~108°, ideal tetrahedral bond angle 109.5°). The tetrahydrofuran ring, being a saturated five membered cyclic ether, attracted chemists due to its presence as a main skeleton in several drugs as well as in natural products. For example, Eribulin Mesylate, Darunavir, Azidothymidine etc. are some of the popular drugs bearing a THF unit. Furthermore, such THF containing compounds are also widely used in the formulation of several perfumes and flavours.Most of the natural products bearing the THF ring as the main skeleton, are derived from plant acetogenins. These acetogenins belong to the Annonaceae family (Custard-apple family) and are considered to be the most potent anti-tumor compounds.

Lees meer

Vergelijk aanbieders (1)

Sorteren op:

€ 33,99 Gratis verzending

Beschrijving (1)

Five membered ring alicyclic compounds are thermodynamically most stable compounds due to their reduced interior angle strain (bond angle is ~108°, ideal tetrahedral bond angle 109.5°). The tetrahydrofuran ring, being a saturated five membered cyclic ether, attracted chemists due to its presence as a main skeleton in several drugs as well as in natural products. For example, Eribulin Mesylate, Darunavir, Azidothymidine etc. are some of the popular drugs bearing a THF unit. Furthermore, such THF containing compounds are also widely used in the formulation of several perfumes and flavours.Most of the natural products bearing the THF ring as the main skeleton, are derived from plant acetogenins. These acetogenins belong to the Annonaceae family (Custard-apple family) and are considered to be the most potent anti-tumor compounds.

Lees meer