Pediatric Liver Disease Diagnosis and Treatment: Evidence-Based Textbook Covering Cholestatic, Metabolic & Inflammatory Hepatobiliary Pathology for GI Fellows

Follow the Pathway from Presentation to Decision - Before the Window ClosesPediatric liver disease turns on pattern recognition under time pressure - the cholestatic neonate who has 45 days before the Kasai window narrows, the infant whose coagulopathy-AFP dissociation points to tyrosinemia before the newborn screen returns, the adolescent whose Coombs-negative hemolysis and falling alkaline phosphatase lock fulminant Wilson disease and demand immediate transplant listing. This reference builds from hepatic embryology and molecular pathophysiology through the full diagnostic and management arc - neonatal cholestasis, genetic cholestatic disorders, metabolic storage diseases, autoimmune and infectious hepatitis, portal hypertension, hepatic tumors, acute liver failure, MASLD, nutritional hepatology, and liver transplantation - connecting mechanism to clinical decision at every step. Forty-eight integrated diagnostic pathways and a consolidated Diagnostic Pathway Master Atlas put structured clinical reasoning at the point of care.What This Book Puts in Your Hands- Exclude biliary atresia within the 45-day Kasai window - the GGT, ultrasound, and biopsy concordance pathway that determines surgical referral without waiting for HIDA scintigraphy.- Recognize Wilson disease behind the mask of autoimmune hepatitis - the AST/ALT ratio, low alkaline phosphatase, and borderline ceruloplasmin pattern that locks the diagnosis before chelation delay causes neurological damage.- Differentiate metabolic liver emergencies in the first week of life - tyrosinemia, GALD, HSV, and mitochondrial hepatopathy separated by their specific biochemical fingerprints.- Subtype genetic cholestatic disorders - BSEP immunohistochemistry, GGT-based differential pathways, and IBAT inhibitor therapy for intractable pruritus.- Stage and manage pediatric MASLD - fibrosis risk stratification, treatment escalation from lifestyle modification through pharmacotherapy and bariatric surgery.- Navigate transplant immunosuppression from induction through long-term maintenance - tacrolimus monitoring, rejection grading, PTLD management, and the adolescent adherence crisis that drives late graft loss.Order your copy and carry the diagnostic pathways that change outcomes for children with liver disease.