Practical Approach Series Human Cytogenetics: A Approach: Volume II: Malignancy and Acquired Abnormalities

Acquired chromosome abnormalities are associated with cancer and leukaemia, exposure to some chemicals and radiation and some rare diseases. This volume is a laboratory manual of techniques for the cytogenetic study of these disorders. Acquired chromosome abnormalities are associated with malignancy, exposure to mutagenic agents, and some chromosome instability syndomes. Their study often entails extensive modification of standard cytogenetic techniques as well as a very different approach to analysis. Human Cytogenetics: A Practical Approach Volume II is the first comprehensive manual of techniques for the study of acquired chromosome abnormalities, and as such will be an invaluable source of information for cytogeneticists, haematologists, and oncologists alike. Since the interpretation of chromosome preparations is notoriously difficult in some of these conditions, illustrations, both diagrammatic and photographic, of all chromosome rearrangements discussed are an important feature of this book. In addition to basic techniques, the book takes a futuristic look at new technology which is becoming important in the study of cytogenetics, particularly in the field of cancer research.