Quantitative Models of the Action Potential

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Bol Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In neurophysiology, several mathematical models of the action potential have been developed, which fall into two basic types. The first type seeks to model the experimental data quantitatively, to reproduce the measurements of current and voltage exactly. The renowned Hodgkin-Huxley model of the axon from the Loligo squid exemplifies such models. Although qualitatively correct, the H-H model does not describe every type of excitable membrane accurately, since it considers only two ions (sodium and potassium), each with only one type of voltage-sensitive channel. However, other ions such as calcium may be important and there is a great diversity of channels for all ions.

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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In neurophysiology, several mathematical models of the action potential have been developed, which fall into two basic types. The first type seeks to model the experimental data quantitatively, to reproduce the measurements of current and voltage exactly. The renowned Hodgkin-Huxley model of the axon from the Loligo squid exemplifies such models. Although qualitatively correct, the H-H model does not describe every type of excitable membrane accurately, since it considers only two ions (sodium and potassium), each with only one type of voltage-sensitive channel. However, other ions such as calcium may be important and there is a great diversity of channels for all ions.


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