Recent Advances in Alzheimer's: Pathogenesis and Therapy

Alzheimer's disease (AD) is a chronic, progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and impaired reasoning. It is the leading cause of dementia in older adults and is marked by the pathological accumulation of amyloid-beta plaques and neurofibrillary tangles. These changes significantly impair daily functioning and quality of life. As the prevalence of AD continues to rise, understanding its pathogenesis and risk factors, improving diagnostic methods, and developing effective therapeutics have become paramount. This work examines the intricate mechanisms underlying AD, explores current diagnostic approaches, and evaluates emerging therapeutic strategies. By elucidating the complexities of AD, it aims to contribute to the growing body of knowledge surrounding this devastating disease.