Growth factors play a pivotal role in signaling the events of tissue formation and repair in the dentin-pulp complex. Therapeutic intervention with recombinant growth factors also provides possibilities for control of cell activity during repair. Harnessing both endogenous and exogenous sources of growth factors can provide exciting opportunities for novel biological approaches to dental tissue repair and the blueprint for the regeneration of the tooth. These approaches offer significant potential for improved clinical management of dental disease and maintenance of tooth vitality.
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