Role of Inflammation in Periodontal Diseases

This book provides an in-depth exploration of the pivotal role inflammation plays in the initiation, progression, and systemic impact of periodontal diseases. It examines how the immune system responds to dysbiotic microbial biofilms and how, when dysregulated, this response leads to chronic inflammation, tissue destruction, and alveolar bone loss.Key chapters cover the molecular mediators of inflammation-such as cytokines, prostaglandins, MMPs, and ROS-and their role in both local tissue damage and broader systemic effects. The transition from acute to chronic inflammation, involving adaptive immune responses, is discussed in detail. It also highlights the growing evidence linking periodontal inflammation to systemic conditions.Combining current scientific understanding with clinical relevance, this volume emphasizes the need for integrative, personalized periodontal care.