Stereotactic Body Radiation Therapy

Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. Stereotactic body radiation therapy (SBRT) has emerged as an innovative treatment for various primary and metastatic cancers, and the past five years have witnessed a quantum leap in its use. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists. Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

This book serves as a practical guide for the use of stereotactic body radiation therapy in clinics. On the basis of more than 10 years of clinical experience with lung cancer, liver cancer and other cancers, a remarkable volume of knowledge has been accumulated. At the same time, great progress in techniques has been achieved. Various new fixing apparatuses, new respiratory regulation techniques, new dose fractionation schedules and new image-guided radiation therapy machines have been developed. This book reviews the history of those developments and reports on various types of toxicities. Review of recent clinical studies is also included. The authors were key members of the JCOG 0403 clinical trials on stereotactic body radiation therapy (SBRT) for both inoperable and operableT1N0M0 primary lung cancer. Readers will learn of the superior outcomes obtained with SBRT for lung cancer and other cancers in terms of local control and toxicities. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists and senior nurses as well as medical oncologists and surgical oncologists who are interested in radiotherapy.