T Cell Biology - From Development to Immunotherapy: Immunotherapy

T lymphocytes are master regulators of adaptive immunity, and understanding their biology is essential for advancing immunotherapy, vaccine development, and the treatment of immune-mediated diseases. This volume offers a comprehensive and up-to-date exploration of T cell biology, from thymic development and TCR signaling to the functional specialization of T cell subsets. The book bridges fundamental immunology and translational applications, covering T cell involvement in autoimmunity, cancer, infectious diseases, and immunodeficiencies, as well as groundbreaking topics such as CAR-T cell therapy, TCR gene editing, and emerging technologies including single-cell analysis and spatial transcriptomics. Written by experts in the field, this book provides an accessible yet rigorous synthesis of current knowledge. It is an essential resource for immunologists, cancer researchers, graduate students, and clinician-scientists seeking to deepen their understanding of T cell biology and its therapeutic potential.