Tackling Antibiotic Resistance: Combating Bacterial Infections

Antibiotic resistance, the so called silent pandemic, is a serious, global health concern that has already cost Millions of lives. This book provides strategies for combatting antibiotic resistance by discussing strategies and methods to deal with the evolution of resistance, and potential applications of alternative strategies. Antibiotic resistance, the so called silent pandemic, is a serious, global health concern that has already cost Millions of lives. This book provides strategies for combatting antibiotic resistance by presenting in depth reviews of the nature and seriousness of the issue and discussing strategies and methods to deal with the evolution of resistance. Chapters unlock potential applications of alternative strategies. Comprehensive and updated information is presented for readers. For example, use of nanomaterial as antimicrobials to cure infections caused by superbugs or use of artificial intelligence and machine learning for overall control of antibiotic resistance in bacteria. Antibiotic stewardship programs are amongst the key strategies to control antibiotic resistance in bacteria. A review of an ideal stewardship program is presented. In addition, promising role of bacteriophages, antibacterial peptides, CRISPR-Cas systems and aptamers are reviewed in separate chapters with current update on research and developments, drugs in pipeline as well as future perspectives.