ADVANCED PRACTICE OF PRECISION MEDICINE: A Clinical Guide to Genomics, Biomarkers, Pharmacogenomics, Targeted Therapies, And Individualized Patient Care.

Precision medicine is reshaping clinical care, yet interpreting genomic findings and converting molecular evidence into safe treatment decisions remains challenging for many healthcare professionals.ADVANCED PRACTICE OF PRECISION MEDICINE bridges the gap between genomic science and real-world clinical application. Written for clinicians, medical fellows, advanced practice providers, pharmacists, genetic counsellors, and advanced healthcare students, this authoritative reference presents the scientific foundations, decision frameworks, and implementation strategies needed to apply precision medicine across major clinical specialties.Inside, readers will explore: - Next-generation sequencing, whole-exome sequencing, and whole-genome sequencing- Clinical bioinformatics and genomic test selection- ACMG/AMP variant classification and interpretation- Hereditary cancer syndromes and cascade testing- Precision oncology, targeted therapies, and companion diagnostics- Liquid biopsy, circulating tumour DNA, and resistance monitoring- Pharmacogenomic prescribing and CPIC guidance- Rare and undiagnosed disease genomics- Polygenic risk scores and disease prediction- Reproductive, prenatal, paediatric, cardiovascular, and neurological genomics- Epigenomics, gene therapy, multi-omics, and emerging clinical technologies- Ethical practice, health equity, clinical documentation, and health-system implementationEach chapter connects molecular evidence with clinical reasoning, patient communication, multidisciplinary care, and quality improvement. The material is organised for advanced study, fellowship teaching, genomic case conferences, molecular tumour boards, and point-of-care consultation.Develop the knowledge needed to evaluate genomic reports, assess molecular evidence, select appropriate tests, interpret clinically actionable findings, and integrate precision medicine into individualised patient care.