FOUNDATIONS OF PRECISION MEDICINE: Genomics, Biomarker-Guided Diagnosis, Targeted Therapy, and Individualized Patient Care

What if medical treatment could be selected not only for a disease, but for the molecular characteristics of the individual patient?FOUNDATIONS OF PRECISION MEDICINE offers a clinically focused introduction to the genomic technologies, biomarkers and targeted interventions reshaping modern healthcare. It connects molecular science with real clinical decision-making, helping readers understand how genomic information moves from the laboratory into diagnosis, treatment selection and individualized patient care.Develop the knowledge needed to interpret genomic findings, evaluate biomarker-guided therapies and understand why patients with the same diagnosis may respond differently to treatment. This textbook makes a rapidly developing field more accessible without separating scientific principles from their clinical purpose.Readers will explore how precision medicine is applied across oncology, inherited disorders, cardiology, reproductive medicine, infectious disease, pharmacology and rare-disease care.Across 20 structured chapters, the book examines: - Next-generation, whole-exome and whole-genome sequencing- Germline and somatic variant interpretation- Clinical genomic reports and genetic counselling- Hereditary cancer testing and risk management- Tumour profiling and molecular tumour boards- Kinase inhibitors and biomarker-guided targeted therapy- Immuno-oncology and checkpoint-inhibitor biomarkers- Pharmacogenomics and individualized drug dosing- Liquid biopsy and circulating tumour DNA- CRISPR, gene editing and viral-vector therapies- Rare and inherited diseases- Proteomics, metabolomics and multi-omics integration- Artificial intelligence and machine learning in genomics- Prenatal, neonatal and cardiovascular genomics- Pathogen sequencing and antimicrobial stewardship- Ethics, genomic equity and clinical implementationNumbered learning objectives support systematic study, while reference appendices cover companion diagnostics, pharmacogenomic gene-drug pairs and molecular testing platforms. A detailed medical glossary supports revision and point-of-care reference.Designed for clinicians, medical trainees, biomedical scientists, genomic professionals and healthcare researchers, FOUNDATIONS OF PRECISION MEDICINE provides a structured route from foundational genomic science to evidence-informed clinical application.Build the genomic literacy needed to understand molecular reports, assess targeted treatments and participate confidently in the future of individualized healthcare.